The best Side of ceesdekker
The best Side of ceesdekker
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Human Rad51 filaments on double- and one-stranded DNA: correlating standard and irregular kinds with recombination operate.
The following content articles are merged in Scholar. Their merged citations are counted only for the primary short article.
However, for years soon after Iijima’s report, the production of cleanse nanotubes was cumbersome. In 1996, nevertheless, the team of Richard Smalley at Rice College managed to produce solitary-walled carbon nanotubes at high produce. Soon following, I contacted Smalley, and we chose to sign up for forces to measure the transport via a single carbon nanotube.
2012, discovery that nucleoid occlusion underlies the precision of bacterial mobile division; and very first at any time examine of your dynamics DNA supercoils and the discovery of supercoil hopping
Experimental period diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
You are a Christian. If you could possibly make this type of artificial cell, would you be one action closer to God, or would the purpose of God have diminished to some degree once again?
He also observed time to write various books, send out Just about forty thousand tweets and lead An effective investigate group at Delft College of Technology. ‘It doesn’t come cees dekker to feel like work’, he states. ‘I’m just terribly curious.’
Comprehension fundamental processes regulating the spatial and dynamic organisation in the DNA in Stay cells.
Pretty neat, but that wasn’t truly where my interest lay. I needed to pioneer And that i had the feeling that was not attainable, because the most interesting elementary insights experienced by now been uncovered. But my area experienced designed quite a few exciting new equipment to measure personal molecules. I decided which i planned to use this to biology, to look at it from a Actual physical viewpoint.’
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
Cees Dekker is Distinguished University Professor at TU Delft. Educated being a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes inside the nineties. Given that 2000, he moved to solitary-molecule biophysics and nanobiology. His latest study focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker can be an elected member of the KNAW and fellow to the APS as well as IOP.
2005, discovery of the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-range conformational changes in Mre11/DNA repair complexes; and initially pressure measurements with a DNA molecule in the nanopore
It was an exceedingly appealing time, all through which I gained lots of guidance from Delft University of Technologies, exactly where I had been a professor at time, And that i commenced a number of collaborations with molecular biologists. That served me master a great deal.’